A mission can be defeated either of two ways: by damaging the villain or by fulfilling the mission’s “defeat” condition. Each defeat condition is different (and some villains cannot be tricked into defeat in this fashion), but involves performing an action: and paying the necessary costs (discarding cards, charging powers, etc). More commonly, a hero can simply their attacks to defeat the villain – a hero that reduces the villain’s hit points to zero defeats the villain, completing the mission.

When a mission is completed, the hero who completes the mission places the mission card under himself to show the mission is complete. There is a global “Victory” prize that all of the players receive from the mission card now that Paragon is safe from the villain’s plot. The victorious hero receives no special reward for his thankless work, but there are other cards available that provide special bonuses for completed missions.